Sport- und physiotherapeutische Maßnahmen zur Behandlung der chronischen Graft-versus-Host-Krankheit

Zusammenfassung

Hintergrund Patienten mit chronischer Graft-versus-Host-Krankheit (cGvHD) nach allogener hämatopoetischer Stammzelltransplantation (alloSZT) leiden oft langfristig an reduzierter Leistungsfähigkeit und Bewegungseinschränkungen.

Methoden Durch die Arbeitsgruppe des German-Austrian-Swiss GvHD-Konsortium wurde in Kooperation mit Physiotherapeuten, Sportwissenschaftlern, Pädiatern, Pneumologen und Rehabilitationsmedizinern ein Konsens zur Bewegungstherapie der GvHD erarbeitet.

Ergebnisse Trotz regelmäßiger Anwendung physio- und sporttherapeutischer Maßnahmen in der Supportivtherapie der cGvHD, ist die Datenlage limitiert. Um die Qualität der Behandlung von cGvHD-Patienten durch die Etablierung einheitlicher Standards zu verbessern, wurde ein Konsens erarbeitet.

Diskussion und Schlussfolgerung Die Verbesserung der Leistungsfähigkeit und Lebensqualität von cGvHD-Patienten erfordert eine kontinuierliche Therapie und die Validierung der Konsensusempfehlungen.

Abstract

Summary Purpose Patients with chronic graft-versus-host-disease (cGvHD) after allogeneic hematopoietic stem cell transplantation (alloSCT) may suffer from reduced physical performance and mobility restriction for a long time.

Methods The German-Austrian-Swiss cGvHD-consortium developed in cooperation with physiotherapists, sport therapists, pediatricians, pulmonologists and rehabilitation physicians consensus recommendations for exercise therapy in cGvHD.

Results Despite regular application of physio- and sports therapy in the treatment of cGvHD, the published evidence is limited. Therefore, we developed consensus recommendations in order to improve the quality of treatment of cGvHD-patients by establishing uniform standards.

Discussion and conclusions In order to further improve the performance and QoL of cGvHD-patients, continuous therapy and the validation of the consensus recommendations are warranted.

Schlüsselwörter

allogene hämatopoetische Stammzelltransplantation - Graft-versus-Host Erkrankung - Physiotherapie - Sporttherapie - Rehabilitation

Key words

allogeneic hematopoietic stem cell transplantation - graft-versus-host disease - physiotherapy - sport therapy - rehabilitation

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