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Klin Padiatr 2018; 230(06): 330-332
DOI: 10.1055/a-0594-9362
Short Communication
© Georg Thieme Verlag KG Stuttgart · New York

Spectrum of Parvovirus B19 Infection Presentations in Children with Underlying Hemato-oncologic Disorders: A Case Series

Spektrum von klinischen Präsentationen der Parvovirus B19 Infektion in Kindern mit Hämato-Onkologische Erkrankungen: Eine Fallserie
Aida Zečkanović
2   Department for Pediatric Hematology and Oncology, University Children’s Hospital of Ljubljana, Ljubljana, Slovenia
,
Matej Perovnik
1   Faculty of Medicine, Ljubljana, University of Ljubljana, Slovenia
,
Janez Jazbec
2   Department for Pediatric Hematology and Oncology, University Children’s Hospital of Ljubljana, Ljubljana, Slovenia
,
Marko Kavčič
2   Department for Pediatric Hematology and Oncology, University Children’s Hospital of Ljubljana, Ljubljana, Slovenia
› Author Affiliations
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Publication History

Publication Date:
16 April 2018 (online)

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Introduction

Parvovirus B19 (PVB19) infection is common in childhood and is usually asymptomatic or presents with erythema infectiosum (Young et al., New England Journal of Medicine 2004; 350: 586–597). In patients with decreased erythrocyte lifespan it can cause a transient aplastic crisis, with non-specific viral symptoms and anemia (Young et al., New England Journal of Medicine 2004; 350: 586–597, Servey et al., Am Fam Physician 2007; 75: 373–376). Immunocompromised hosts may develop chronic red cell aplasia, with severe anemia and persistent or recurrent viremia and symptoms of fatigue and pallor (Young et al., New England Journal of Medicine 2004; 350: 586–597, Servey et al., Am Fam Physician 2007; 75: 373–376). We aim to raise awareness about atypical clinical presentations of PVB19 infection in children with hemato-oncological conditions.

We present two cases of PVB19 infection in children with hereditary spherocytosis and 2 cases in immunocompromised oncology patients.