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CC BY-NC-ND 4.0 · Rev Bras Ortop (Sao Paulo) 2019; 54(01): 001-005
DOI: 10.1016/j.rbo.2017.06.025
Review Article | Artigo de Revisão
Sociedade Brasileira de Ortopedia e Traumatologia. Published by Thieme Revnter Publicações Ltda Rio de Janeiro, Brazil

Tromboprofilaxia na artroplastia total do joelho[*]

Article in several languages: português | English
Julio Cesar Gali 
1   Departamento de Ortopedia, Faculdade de Ciências Médicas e da Saúde, Pontifícia Universidade Católica de São Paulo (PUC-SP), Sorocaba, SP, Brasil
,
Danilo Bordini Camargo
1   Departamento de Ortopedia, Faculdade de Ciências Médicas e da Saúde, Pontifícia Universidade Católica de São Paulo (PUC-SP), Sorocaba, SP, Brasil
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Further Information

Publication History

04 June 2017

27 June 2017

Publication Date:
01 March 2019 (online)

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Resumo

Os autores descrevem uma atualização dos principais métodos de prevenção da trombose venosa profunda após artroplastia total do joelho, classificados em métodos mecânicos e farmacológicos. Reportam as principais drogas usadas, dosagem, riscos e benefícios comparativos.

Palavras-chave

prótese total de joelho - complicações - trombose venosa - prevenção

* Trabalho desenvolvido no Departamento de Ortopedia, Faculdade de Ciências Médicas e da Saúde, Pontifícia Universidade Católica de São Paulo (PUC-SP), Sorocaba, SP, Brasil. Publicado originalmente por Elsevier Editora Ltda. © 2018 Sociedade Brasileira de Ortopedia e Traumatologia.


 

  • Referências

  • 1 Song K, Xu Z, Rong Z, Yang X, Yao Y, Shen Y. , et al. The incidence of venous thromboembolism following total knee arthroplasty: a prospective study by using computed tomographic pulmonary angiography in combination with bilateral lower limb venography. Blood Coagul Fibrinolysis 2016; 27 (03) 266-9
    CrossrefPubMedGoogle Scholar
  • 2 Blanchard J, Meuwly JY, Leyvraz PF, Miron MJ, Bounameaux H, Hoffmeyer P. , et al. Prevention of deep-vein thrombosis after total knee replacement. Randomised comparison between a low-molecular-weight heparin (nadroparin) and mechanical prophylaxis with a foot-pump system. J Bone Joint Surg Br 1999; 81 (04) 654-9
    CrossrefPubMedGoogle Scholar
  • 3 Lachiewicz PF, Kelley SS, Haden LR. Two mechanical devices for prophylaxis of thromboembolism after total knee arthroplasty. A prospective, randomised study. J Bone Joint Surg Br 2004; 86 (08) 1137-41
    PubMedGoogle Scholar
  • 4 He ML, Xiao ZM, Lei M, Li TS, Wu H, Liao J. Continuous passive motion for preventing venous thromboembolism after total knee arthroplasty. Cochrane Database Syst Rev 2014; (07) CD008207
    PubMedGoogle Scholar
  • 5 Barrack RL. Current guidelines for total joint VTE prophylaxis: dawn of a new day. J Bone Joint Surg Br 2012; 94 (11, Suppl A): 3-7
    CrossrefPubMedGoogle Scholar
  • 6 Parvizi J, Jacovides CL, Bican O, Purtill JJ, Sharkey PF, Hozack WJ. , et al. Is deep vein thrombosis a good proxy for pulmonary embolus?. J Arthroplasty 2010; 25 (6, Suppl) 138-44
    PubMedGoogle Scholar
  • 7 Jacobs JJ, Mont MA, Bozic KJ, Della Valle CJ, Goodman SB, Lewis CG. , et al. American Academy of Orthopaedic Surgeons clinical practice guideline on: preventing venous thromboembolic disease in patients undergoing elective hip and knee arthroplasty. J Bone Joint Surg Am 2012; 94 (08) 746-7
    CrossrefPubMedGoogle Scholar
  • 8 Lotke PA, Lonner JH. The benefit of aspirin chemoprophylaxis for thromboembolism after total knee arthroplasty. Clin Orthop Relat Res 2006; 452 (452) 175-80
    CrossrefPubMedGoogle Scholar
  • 9 Callaghan JJ, Warth LC, Hoballah JJ, Liu SS, Wells CW. Evaluation of deep venous thrombosis prophylaxis in low-risk patients undergoing total knee arthroplasty. J Arthroplasty 2008; 23 (06) (Suppl. 01) 20-4
    PubMedGoogle Scholar
  • 10 Bozic KJ, Vail TP, Pekow PS, Maselli JH, Lindenauer PK, Auerbach AD. Does aspirin have a role in venous thromboembolism prophylaxis in total knee arthroplasty patients?. J Arthroplasty 2010; 25 (07) 1053-60
    CrossrefPubMedGoogle Scholar
  • 11 Parvizi J, Huang R, Restrepo C, Chen AF, Austin MS, Hozack WJ. , et al. Low-Dose Aspirin Is Effective Chemoprophylaxis Against Clinically Important Venous Thromboembolism Following Total Joint Arthroplasty: A Preliminary Analysis. J Bone Joint Surg Am 2017; 99 (02) 91-8
    CrossrefPubMedGoogle Scholar
  • 12 Liu F, Chu X, Huang J, Tian K, Hua J, Tong P. Administration of enoxaparin 24 h after total knee arthroplasty: safer for bleeding and equally effective for deep venous thrombosis prevention. Arch Orthop Trauma Surg 2014; 134 (05) 679-83
    CrossrefPubMedGoogle Scholar
  • 13 Arsoy D, Giori N, Woolson S. Mechanical Compression Reduces Readmissions and Wound Complications from Low Molecular Weight Heparin after Total Hip or Knee Arthroplasty. San Diego: AAOS Annual Meeting; 2017
    PubMedGoogle Scholar
  • 14 Bauer KA, Eriksson BI, Lassen MR, Turpie AG. ; Steering Committee of the Pentasaccharide in Major Knee Surgery Study. Fondaparinux compared with enoxaparin for the prevention of venous thromboembolism after elective major knee surgery. N Engl J Med 2001; 345 (18) 1305-10
    CrossrefPubMedGoogle Scholar
  • 15 Lassen MR, Ageno W, Borris LC, Lieberman JR, Rosencher N, Bandel TJ. , et al; RECORD3 Investigators. Rivaroxaban versus enoxaparin for thromboprophylaxis after total knee arthroplasty. N Engl J Med 2008; 358 (26) 2776-86
    CrossrefPubMedGoogle Scholar
  • 16 Levitan B, Yuan Z, Turpie AG, Friedman RJ, Homering M, Berlin JA. , et al. Benefit-risk assessment of rivaroxaban versus enoxaparin for the prevention of venous thromboembolism after total hip or knee arthroplasty. Vasc Health Risk Manag 2014; 10 (10) 157-67
    PubMedGoogle Scholar
  • 17 Bloch BV, Patel V, Best AJ. Thromboprophylaxis with dabigatran leads to an increased incidence of wound leakage and an increased length of stay after total joint replacement. Bone Joint J 2014; 96-B (01) 122-6
    PubMedGoogle Scholar
  • 18 Yoshida RA, Yoshida WB, Rollo HA. Novos anticoagulantes orais para a profilaxia e tratamento do tromboembolismo venoso em cirurgias ortopédicas de grande porte. J Vasc Bras 2011; 10 (02) 145-53
    CrossrefGoogle Scholar
  • 19 Raskob GE, Gallus AS, Pineo GF, Chen D, Ramirez LM, Wright RT. , et al. Apixaban versus enoxaparin for thromboprophylaxis after hip or knee replacement: pooled analysis of major venous thromboembolism and bleeding in 8464 patients from the ADVANCE-2 and ADVANCE-3 trials. J Bone Joint Surg Br 2012; 94 (02) 257-64
    CrossrefPubMedGoogle Scholar
  • 20 Gómez-Outes A, Terleira-Fernández AI, Suárez-Gea ML, Vargas-Castrillón E. Dabigatran, rivaroxaban, or apixaban versus enoxaparin for thromboprophylaxis after total hip or knee replacement: systematic review, meta-analysis, and indirect treatment comparisons. BMJ 2012; 344: e3675
    CrossrefPubMedGoogle Scholar
  • 21 Revankar N, Patterson J, Kadambi A, Raymond V, El-Hadi W. A Canadian study of the cost-effectiveness of apixaban compared with enoxaparin for post-surgical venous thromboembolism prevention. Postgrad Med 2013; 125 (04) 141-53
    CrossrefPubMedGoogle Scholar
  • 22 Fuji T, Wang CJ, Fujita S, Kawai Y, Nakamura M, Kimura T. , et al. Safety and efficacy of edoxaban, an oral factor Xa inhibitor, versus enoxaparin for thromboprophylaxis after total knee arthroplasty: the STARS E-3 trial. Thromb Res 2014; 134 (06) 1198-204
    CrossrefPubMedGoogle Scholar
  • 23 Turpie AG, Bauer KA, Davidson BL, Fisher WD, Gent M, Huo MH. , et al; EXPERT Study Group. A randomized evaluation of betrixaban, an oral factor Xa inhibitor, for prevention of thromboembolic events after total knee replacement (EXPERT). Thromb Haemost 2009; 101 (01) 68-76
    Article in Thieme ConnectPubMedGoogle Scholar
  • 24 Parvizi J, Huang R, Raphael IJ, Maltenfort MG, Arnold WV, Rothman RH. Timing of Symptomatic Pulmonary Embolism with Warfarin Following Arthroplasty. J Arthroplasty 2015; 30 (06) 1050-3
    CrossrefPubMedGoogle Scholar
  • 25 Miyagi J, Funabashi N, Suzuki M, Asano M, Kuriyama T, Komuro I. , et al. Predictive indicators of deep venous thrombosis and pulmonary arterial thromboembolism in 54 subjects after total knee arthroplasty using multislice computed tomography in logistic regression models. Int J Cardiol 2007; 119 (01) 90-4
    CrossrefPubMedGoogle Scholar
  • 26 Bohl DD, Maltenfort MG, Huang R, Parvizi J, Lieberman JR, Della Valle CJ. Development and Validation of a Risk Stratification System for Pulmonary Embolism After Elective Primary Total Joint Arthroplasty. J Arthroplasty 2016; 31 (9, Suppl) 187-91
    CrossrefPubMedGoogle Scholar
  • 27 Plante S, Belzile EL, Fréchette D, Lefebvre J. Analysis of contributing factors influencing thromboembolic events after total knee arthroplasty. Can J Surg 2017; 60 (01) 30-6
    PubMedGoogle Scholar
  • 28 Newman JM, Abola MV, Macpherson A, Klika AK, Barsoum WK, Higuera CA. ABO Blood Group Is a Predictor for the Development of Venous Thromboembolism After Total Joint Arthroplasty. J Arthroplasty 2017; 32 (9S): S254-8
    CrossrefPubMedGoogle Scholar