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CC BY-NC-ND 4.0 · Journal of Coloproctology 2015; 35(03): 146-150
DOI: 10.1016/j.jcol.2015.02.010
Original Article

Is prevalence of colorectal polyps higher in patients with family history of colorectal cancer?

A prevalência de pólipos colorretais é mais elevada em pacientes com história familiar de câncer colorretal?
Sthela Maria Murad-Regadas
a   Department of Surgery, Medicine School, Universidade Federal do Ceará (UFC), Fortaleza, CE, Brazil
b   Sector of Anorectal and Pelvic Floor Physiology, Hospital das Clínicas, Medicine School, Universidade Federal do Ceará (UFC), Fortaleza, CE, Brazil
,
Carla Camila Rocha Bezerra
c   Service of Coloproctology, Hospital Universitário Walter Cantídeo, Universidade Federal do Ceará (UFC), Fortaleza, CE, Brazil
,
Ana Ligia Rocha Peixoto
d   Service of Coloproctology, Hospital Regional do Cariri, Juazeiro do Norte, CE, Brazil
,
Francisco Sérgio Pinheiro Regadas
a   Department of Surgery, Medicine School, Universidade Federal do Ceará (UFC), Fortaleza, CE, Brazil
,
Lusmar Veras Rodrigues
a   Department of Surgery, Medicine School, Universidade Federal do Ceará (UFC), Fortaleza, CE, Brazil
e   Service of Coloproctology, Medicine School, Universidade Federal do Ceará (UFC), Fortaleza, CE, Brazil
,
José Airton Gonçalves Siebra
c   Service of Coloproctology, Hospital Universitário Walter Cantídeo, Universidade Federal do Ceará (UFC), Fortaleza, CE, Brazil
,
Graziela Olivia da Silva Fernandes
c   Service of Coloproctology, Hospital Universitário Walter Cantídeo, Universidade Federal do Ceará (UFC), Fortaleza, CE, Brazil
,
Rafael Aragão Vasconcelos
c   Service of Coloproctology, Hospital Universitário Walter Cantídeo, Universidade Federal do Ceará (UFC), Fortaleza, CE, Brazil
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Abstract

Objectives To assess the prevalence of polyps in patients with a family history of colorectal cancer, in comparison to asymptomatic individuals with indication for screening.

Methods A prospective study in a group of patients who underwent colonoscopy between 2012 and 2014. Patients were divided into two groups: Group I: no family history of colorectal cancer, and Group II: with a family history in first-degree relatives. Demographic characteristics, findings on colonoscopy, presence, location and histological type of polyps were evaluated, comparing the two groups.

Results 214 patients were evaluated: 162 in Group I and 52 in Group II. The distribution of patients with polyps was similar in relation to gender: polyps were evidenced in Group I in 33 (20%) female patients vs. 10 (6%) male patients (p = 1.00); in Group II, the presence of polyps was evidenced in 9 (17%) female patients vs. 2 (4%) male patients (p = 1.00). Polypoid lesions were found in 54 patients (25%), with 43 (26%) in Group I and 11 (21%) in Group II. The prevalence of adenomas was similar in both groups (Group I = 18/37% vs. Group II = 10/50%) (p = 0.83).

Conclusion In this preliminary study, no correlation was found between prevalence of polyps and a family history of colorectal cancer.

Resumo

Objetivos Avaliar a prevalência de pólipos em pacientes com história familiar de câncer colorretal comparando com indivíduos assintomáticos com indicação para rastreamento.

Métodos Estudo prospectivo realizado em um grupo de indivíduos submetidos à colonoscopia entre 2012 e 2014. Os pacientes foram distribuídos em dois grupos: Grupo I: sem história familiar de câncer colorretal e Grupo II: com história familiar em parentes de primeiro grau. Avaliaram-se características demográficas, achados na colonoscopia, presença, localização e tipo histológico dos pólipos, comparando os dois grupos.

Resultados Foram avaliados 214 pacientes, 162 incluídas no grupo I e 52 no grupo II. A distribuição dos pacientes com pólipos foi similar em relação ao sexo, sendo evidenciado pólipos no Grupo I em 33 (20%) pacientes do sexo feminino vs. 10 (6%) masculino (p = 1,00) e no Grupo II, presença de pólipos em pacientes do sexo feminino em 9 (17%) vs. 2 (4%) masculino (p = 1,00). Foram encontradas lesões polipóides em 54 pacientes (25%), sendo 43 (26%) no grupo I e 11 (21%) no grupo II. A prevalência de adenomas foi similar em ambos os grupos (Grupo I = 18/37% vs. Grupo II = 10/50%) (p = 0,83).

Conclusão Neste estudo inicial, não foi encontrada correlação entre a prevalência de pólipos e o histórico familiar de câncer colorretal.

Keywords

Colonoscopy - Polyps - Prevention - Colorectal cancer

Palavras-chave

Videocolonoscopia - Pólipos - Prevenção - Câncer colorretal


Publication History

Received: 29 December 2014

Accepted: 20 February 2015

Article published online:
17 February 2021

© 2015. Sociedade Brasileira de Coloproctologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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