MCQs: International Journal of Epilepsy*

Questions

1. The Atkins diet was developed by Robert Atkins in 1970 and was later modified for use in people with refractory epilepsy. Which of the following is not a characteristic feature of the Modified Atkins Diet?

   • a.– Protein intake is not restricted

   • b.– Carbohydrate is restricted to 10–20 g/day

   • c.– Ketogenic ration is 3:1

   • d.– It has about 10% carbohydrates

2. A 70 years old gentleman presented to the Emergency Department with epilepsia partialis continua involving the right hand and thumb. Blood glucose was 700 mg/dl, serum sodium was 124 mEq/L and MRI brains including diffusion weighted images were normal. Which of the following is the most likely condition responsible for the patient's condition?

   • a.– Stroke

   • b.– Non-ketotic hyperglycemia of diabetes

   • c.– Diabetic keto-acidosis

   • d.– Hyponatremia

3. Negative motor seizures are rare and can be confused with transient ischemic attacks (TIA). Which of the following points differentiates between the two conditions?

   • a.– Both conditions typically occur in elderly people

   • b.– Spread of symptoms is characteristic of TIAs but does not occur in negative motor seizures

   • c.– TIAs might last for more than few minutes but negative motor seizures are brief

   • d.– TIAs might be associated with focal limb weakness but negative motor seizures are definitely not associated with focal limb weakness.

4. The EEG page and MRI below is of a 12 months old baby. The likely diagnosis is:

   • a.– Lissencephaly

   • b.– Hydranencephaly

   • c.– Double cortex syndrome

   • d.– Rud syndrome

5. Which of the following is not true regarding outcome in status epilepticus?

   • a.– Mortality is high is refractory status epilepticus

   • b.– Mortality is associated with the need for mechanical ventilation

   • c.– Acute symptomatic status epilepticus is associated with an excellent outcome and low mortality

   • d.– Mortality depends on the time lag between onset and presentation in the Emergency Department

6. Which of the following statements is not true regarding the co-morbidity of Epilepsy and Depression?

   • a.– Depression is twice as common in people with epilepsy in comparison to people with asthma

   • b.– Depression contributes to impaired quality of life in people with epilepsy

   • c.– Major depression might occur with increased frequency in people with epilepsy on Carbamazepine, Oxycarbazepine and Lamotrigine

   • d.– Poor seizure control is associated with increased incidence of major depression

7. Epilepsy with which of the following inborn errors of metabolism is exquisitely responsive to ketogenic diet?

   • a.– Pyruvate carboxylase deficiency

   • b.– GLUT-1 deficiency

   • c.– Fatty acid oxidation disorder

   • d.– Porphyria

8. Fractional anisotropy is utilized in diffusion tensor imaging. Which of the following is not correct about fractional anisotropy?

   • a.– It refers to the degree of anisotropy of a diffusion process

   • b.– It is a scalar value between zero and one

   • c.– It is depended on fiber density axonal diameter and myelination of fiber tracts

   • d.– A value of one means that diffusion is unrestricted

9. Features associated with inborn errors of metabolism in children with epilepsy include all of the following except:

   • a.– Abnormal urine odour (in GLUT-1 deficiency)

   • b.– Hair and nail abnormalities in Menkes disease

   • c.– Albinism in phenylketonuria

   • d.– Macrosomia in GABA transaminase deficiency

10. The estimated number of people with epilepsy worldwide is

    • a.– 50,000,000

    • b.– 100,000,000

    • c.– 75,00,000

    • d.– 50,00,000

This MCQ has been prepared from the first issue of IJEP 2014 to maintain continuity in updates in knowledge one acquired from the earlier issue.