Homeopathy 2012; 101(03): 165-170
DOI: 10.1016/j.homp.2012.02.007
Original Paper
Copyright © The Faculty of Homeopathy 2012

Toxicodendron pubescens retains its anti-arthritic efficacy at 1M, 10M and CM homeopathic dilutions

Dhanraj Ramanlal Patel
Imtiyaz Ahmed Ansari
Yasin Nasir Kachchhi
Rachna Bipinchandra Patel
Kalpesh Ramdas Patil
Ramchandra Baburao Jadhav
Chandragouda Raosaheb Patil

Subject Editor:
Further Information

Publication History

Received19 January 2012

accepted15 February 2012

Publication Date:
29 December 2017 (online)

Background: Our previous studies of Toxicodendron pubescens (Rhus tox) in homeopathic dilutions have shown anti-inflammatory activity in line with the principle of similia. The present study aimed to evaluate its anti-inflammatory activity in 1M, 10M and CM dilutions in rats.

Method: Arthritis was induced by subplantar injection of 0.1 ml of Complete Freund’s Adjuvant (CFA) in the right hind paws of rats. The severity of inflammatory lesions was measured plethysmometrically on 21st day post CFA injection. The intensity of pain was measured using digital Von Frey apparatus. Other estimations included serum C-reactive protein (CRP), hematological parameters, body weight changes, arthritic pain score and radiological analysis of the arthritic paws.

Result: The 1M, 10M and CM homeopathic dilutions of Rhus tox reduced primary and secondary arthritic lesions, improved body weight gain and protected rats against CFA-induced hematological and radiological perturbations. A significant reduction in the serum levels of CRP and an improvement in pain threshold of injected paws was observed in the groups treated with the Rhus tox dilutions.

Conclusion: The anti-arthritic potential of Rhus tox is retained at 1M, 10M and CM dilutions.