Homeopathy 2007; 96(02): 95-101
DOI: 10.1016/j.homp.2007.03.001
Original Paper
Copyright © The Faculty of Homeopathy 2007

In vivo study of the anti-inflammatory effect of Rhus toxicodendron

A.L. dos Santos
1  Faculdade de Ciências da Saúde de São Paulo, R. Bartolomeu de Gusmão, São Paulo, São Paulo, Brazil
,
F.F. Perazzo
2  Laboratório de Pesquisa em Fármacos, Centro de Ciências Biológicas e da Saúde, Universidade Federal do Amapá, Rod. JK, km 02, CEP 68902-303, Macapá-AP, Brazil
,
L.G.V. Cardoso
2  Laboratório de Pesquisa em Fármacos, Centro de Ciências Biológicas e da Saúde, Universidade Federal do Amapá, Rod. JK, km 02, CEP 68902-303, Macapá-AP, Brazil
,
J.C.T. Carvalho
2  Laboratório de Pesquisa em Fármacos, Centro de Ciências Biológicas e da Saúde, Universidade Federal do Amapá, Rod. JK, km 02, CEP 68902-303, Macapá-AP, Brazil
› Author Affiliations
Further Information

Publication History

Received12 November 2006
revised02 February 2007

Publication Date:
13 December 2017 (online)

Background Homeopathic Rhus toxicodendron (Rhus tox) is used in various inflammatory conditions. We screened its effect compared to succussed ethanol controls and appropriate active controls.

Method We initially experimented with Rhus tox 6, 12, 30 and 200 cH, using carrageenan-induced paw oedema in rats. The 6 cH dilution appeared most effective and was used in subsequent assays. We used pre-treatment and single treatment regimes in Wistar rats, and mice.

Results We found significant reductions compared to control in carrageenan-induced paw oedema, vascular permeability, writhing induced by intraperitoneal acetic acid and stress induced gastric lesions.

Conclusions Rhus tox in homeopathic dilution appears to interfere with inflammatory processes involving histamine, prostaglandins and other inflammatory mediators.