Homeopathy 2007; 96(01): 22-26
DOI: 10.1016/j.homp.2006.10.004
Original Paper
Copyright © The Faculty of Homeopathy 2006

The use of homeopathic combination remedy for dengue fever symptoms: a pilot RCT in Honduras

J Jacobs
1  Department of Epidemiology, University of Washington, Seattle, Washington, USA
EA Fernandez
2  Environmental Health Program, Ministry of Health, Tegucigalpa, Honduras
B Merizalde
3  American Institute of Homeopathy, Philadelphia, Pennsylvania, USA
GA Avila-Montes
4  Department of Vector-borne disease, Ministry of Health, Tegucigalpa, Honduras
D Crothers
5  Evergreen Center for Homeopathic Medicine, Edmonds, Washington, USA
› Author Affiliations
Further Information

Publication History

Received11 July 2006
revised20 October 2006

accepted30 October 2006

Publication Date:
13 December 2017 (online)


A double-blind, placebo-controlled randomized trial of a homeopathic combination medication for dengue fever was carried out in municipal health clinics in Honduras. Sixty patients who met the case definition of dengue (fever plus two ancillary symptoms) were randomized to receive the homeopathic medication or placebo for 1 week, along with standard conventional analgesic treatment for dengue. The results showed no difference in outcomes between the two groups, including the number of days of fever and pain as well as analgesic use and complication rates. Only three subjects had laboratory confirmed dengue. An interesting sinusoidal curve in reported pain scores was seen in the verum group that might suggest a homeopathic aggravation or a proving. The small sample size makes conclusions difficult, but the results of this study do not suggest that this combination homeopathic remedy is effective for the symptoms that are characteristic of dengue fever.