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‘Cure’ as the gold standard for likelihood ratio assessment: theoretical considerations
Received13 October 2003
revised10 February 2004
accepted01 March 2004
19 December 2017 (online)
A gold standard is necessary to assess the validity of homeopathic symptoms. The gold standard is ‘cure’, but this is difficult to define, and depends on consensus. The likelihood ratio (LR) method will give valid results only if the gold standard is reliable. False positives (patients incorrectly classified as cured) weaken results of LR investigation. Weakening the standard to enlarge the research population will seriously bias the results. The same gold standard should be used in LR assessment of all symptoms.
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