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Int J Angiol 1996; 5(3): 144-148
DOI: 10.1007/BF02043211
Original Articles

© Georg Thieme Verlag KG Stuttgart · New York

Is the stasis induced by orthostatism a vascular risk factor for arteries as well as for veins?

Paolo Pola, Paolo Tondi, Demetrio De Martini, Laura Gerardino, Sandra De Rossi
  • Department of Angiology, Catholic University of the Sacred Heart, Rome, Italy
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Publication History

Publication Date:
22 April 2011 (online)

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Abstract

Hyperfibrinogenemia is a vascular risk factor influenced by several conditions such as stasis induced by orthostatism. The authors suggest that stasis could also change local fibrinolytic activity. Twenty healthy subjects and 20 patients affected by primary varicose syndrome underwent blood collection from the antecubital vein and from a vein of the lower third of the leg, under baseline conditions, and after a 1 hour orthostatism. Tests for fibrinogenemia, t-PAa and PAI-1a, were carried out. After stasis induced by orthostatism, statistically significant variations of these three parameters were observed in both the control group and the varicose group.