TY - ECHAP DO - 10.1055/sos-SD-228-00166 SN - 9783132423312 SN - 9783132423350 LA - EN AU - Kim,H.; Yoshida,J. TI - 7 Very Fast Reactions and Extreme Conditions PB - Georg Thieme Verlag KG CY - Stuttgart PY - 2018 ET - 1st edition UR - http://www.thieme-connect.com/products/ebooks/lookinside/10.1055/sos-SD-228-00166 T3 - Science of Synthesis VL - 2018/5 DA - 2019/02/01 KW - Keywords: KW - fast reactions KW - unstable intermediates KW - organolithiums KW - extreme conditions KW - high temperature KW - high pressure KW - flow chemistry KW - microreactors KW - flash chemistry AB - Microreaction technology represents a powerful and unique tool for the control of extremely fast reactions and reactions under extreme conditions. In this chapter, fast flow reactions such as Swern–Moffatt oxidations, diisobutylaluminum hydride reductions, reactions involving organolithiums and organomagnesiums, and Friedel–Crafts alkylations are presented. Moreover, this chapter also covers examples of reactions performed under extreme reaction conditions of high temperature and high pressure, which cannot be easily conducted in flasks. T2 - Flow Chemistry in Organic Synthesis ER -