2.13 Base-Metal-Catalyzed Hydrogenation of Polar Unsaturated Bonds

Abstract

The catalytic hydrogenation of carbonyl compounds to afford the corresponding saturated products is of great significance in both organic synthesis and industrial application. Historically, such transformations have generally been based on the use of noble-metal catalysts; however, in recent years, much attention has been paid to the development of earth-abundant-metal catalysts as alternatives to the well-established noble-metal congeners in terms of sustainability. This review comprehensively describes the hydrogenation of carbonyl compounds and related functional groups catalyzed by base metals, including iron, cobalt, manganese, nickel, and copper. These results are expected to promote the further development and prosperity of base-metal catalysis.

Key words

base-metal catalysis - hydrogenation - asymmetric hydrogenation - carbonyl compounds - imines - nitriles - heteroarenes - iron - cobalt - manganese - nickel - copper

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