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Bagley, M. et al.: 2018 Science of Synthesis: Knowledge Updates 2018/3 DOI: 10.1055/sos-SD-130-00273
Knowledge Updates 2018/3

30.6.3 N,N-Acetals (Aminals) (Update 2018)

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Book

Editors: Bagley, M.; Banert, K.; Joule, J. A.; Murai, T.; Ramsden, C. A.

Authors: Aitken, R. A.; Glushkov, V.; González-Bello, C.; Kwiecien, H.; Mutoh, Y.; Nakata, M.; Saikawa, Y.; Shklyaev, Y.

Title: Knowledge Updates 2018/3

Print ISBN: 9783132423213; Online ISBN: 9783132423244; Book DOI: 10.1055/b-006-161208

1st edition © 2018 Thieme. All rights reserved.
Georg Thieme Verlag, Stuttgart

Subjects: Organic Chemistry;Chemical Reactions, Catalysis;Organometallic Chemistry;Laboratory Techniques, Stoichiometry

Science of Synthesis Knowledge Updates



Parent publication

Title: Science of Synthesis

DOI: 10.1055/b-00000101

Series Editors: Carreira, E. M.; Faul, M.; Fürstner, A. (Editor-in-Chief); Kobayashi, S.; Koch, G.; Molander, G.; Nevado, C.; Trost, B. M.; You, S.

Type: Multivolume Edition

Also available at
 

Abstract

This chapter is an update to the earlier Science of Synthesis contribution (Section 30.6) de- scribing methods for the synthesis of N,N-acetals (also known as aminals) that have been reported since 2003. The major recent advances include methods for the enantioselective synthesis of N,N-acetals by organocatalysis and by transition-metal catalysis.

Key words

N,N-acetals - aminals - alkylation - nucleophilic addition - asymmetric catalysis - acid catalysts - electrophilic additions - cycloadditions - hetero-Diels–Alder reactions - imines - palladium catalysts - iridium catalysts
 
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