17.2.1.10 1,2,3-Triazines (Update 2025)

F.-G. Zhang;   J.-A. Ma 

Abstract

1,2,3-Triazines, also sometimes known as v-triazines, are characterized by three contiguous nitrogen atoms in the six-membered ring. Benzo[1,2,3]triazines and heteroarene-fused 1,2,3-triazine derivatives have found applications in drug development(tulrampator). The reactions of 1,2,3-triazine with primary amines, secondary amines, and thiols make them useful labeling molecules within biological systems. This update covers synthetic methods for the preparation 1,2,3-triazines published between 2013 to 2024.

Schlüsselwörter

triazines - diazo compounds - azide compounds - cross-coupling reactions - cyclization reactions - heterocycles

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