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Donohoe, T. J. et al.: 2022 Science of Synthesis, 2022/1: Knowledge Updates 2022/1 DOI: 10.1055/sos-SD-117-00666
Knowledge Updates 2022/1

17.8.5 Porphyrins (Update 2022)

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Editors: Donohoe, T. J.; Krause, N.; Marsden, S. P.; Montchamp, J.-L.; Terent'ev, A. O. ; Weinreb, S. M.

Authors: Ayad, T. ; Barsegyan, Y. ; de Lucca, Jr., E. C. ; Haake, E. ; Hutskalova, V. ; Jux, N. ; Montforts, F.-P. ; Munaretto, L. S. ; Pajkert, R. ; Pirat, J.-L. ; Röschenthaler, G.-V. ; Santana, V. C. S. ; Terent'ev, A. O. ; Tius, M. A. ; Tomkinson, N. C. O. ; Sparr, C. ; Vil’, V. A. ; Virieux, D. 

Title: Knowledge Updates 2022/1

Print ISBN: 9783132451476; Online ISBN: 9783132451490; Book DOI: 10.1055/b000000641

1st edition © 2022. Thieme. All rights reserved.
Georg Thieme Verlag KG, Stuttgart

Subjects: Organic Chemistry;Chemical Reactions, Catalysis;Organometallic Chemistry;Laboratory Techniques, Stoichiometry

Science of Synthesis Knowledge Updates



Parent publication

Title: Science of Synthesis

DOI: 10.1055/b-00000101

Series Editors: Fürstner, A. (Editor-in-Chief); Carreira, E. M.; Faul, M.; Kobayashi, S.; Koch, G.; Molander, G. A.; Nevado, C.; Trost, B. M.; You, S.-L.

Type: Multivolume Edition

Also available at
 


Abstract

This chapter covers methods for the synthesis and transformations of porphyrins, and is an update to the earlier Science of Synthesis contribution Section 17.8.1. The focus is on the literature published in the period 2000–2021. The basic principles and strategies for the construction and modification of the porphyrin core are examined, with an emphasis on the most useful approaches reported in the past two decades.

Key words

porphyrins - pyrroles - macrocycles - natural products - aldehydes - aromaticity - ring closure - total synthesis - acid catalysts - electrophilic substitution - aminoalkylation - Mannich reaction - Vilsmeier formylation
 
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