Bae, Yoon-Soo Cindy et al.: 2023 Procedural Dermatology: Postresidency and Fellowship Compendium, Volume 2 DOI: 10.1055/b-0043-196755

17 Procedural Hair Restoration: Platelet-Rich Plasma for Hair Loss and Hair Transplant

More Information

Book

Editors: Bae, Yoon-Soo Cindy; Ciocon, David H.

Authors: Bae, Gee Young; Bernstein, Leonard J.; Boker, Andreas; Borash, Jordan; Bosley, Rawn; Brauer, Jeremy A.; Brown, Wilfred; Callaghan, Daniel; Chesnut, Cameron; Christman, Mitalee P.; Criscito, Maressa C.; Ebersole, Trina G.; Emer, Jason; Fabi, Sabrina Guillen; Fazzalari, Amanda; Friedman, Adam; Friedmann, Daniel P.; Geronemus, Roy G.; Goldberg, David J.; Gordon, Samantha; Graber, Emmy M.; Hazan, Ezra; Kent, Rhett A.; Khorasani, Hooman; Lederhandler, Margo H.; Lee, Austin; Li, Monica K.; Lin, Richard L.; Lipp, Michael B.; MacGregor, Jennifer L.; Mann, Margaret; Mehrabi, Joseph N.; Mishra, Vineet; Moak, Teri N.; Morton, Laurel M.; Murgia, Robert D.; Murphy, Emily C.; Paul, Benjamin Curman; Robinson, Deanne Mraz; Rokhsar, Cameron; Saedi, Nazanin; Scott, Jeffrey F.; Shridharani, Sachin M.; Soon, Seaver L.; Steele, Robert Blake; Steuer, Alexa B.; Tamashunas, Nina Lucia; Tan, Andrea; Tisch, Grace M.; Wang, Jordan V.; Weiss, Robert; Yeh, Lindsey; Zumwalt, Michael

Title: Procedural Dermatology: Postresidency and Fellowship Compendium, Volume 2

Print ISBN: 9783132424074; Online ISBN: 9783132437142; Book DOI: 10.1055/b000000254

Subjects: Dermatology;Allergology

Thieme Clinical Collections (English Language)



 
Benjamin Curman Paul

Summary

This chapter reviews the most common procedures performed by clinicians treating hair loss. Procedural hair restoration includes the injection of platelet-rich plasma (PRP) to improve the growth and health of the hair and hair transplantation. PRP is an autologous liquid derived from the patient’s blood during an office visit. PRP is rich with growth factors that are used to stimulate the growth and health of the scalp. The major forms of hair transplantation described in this chapter are follicular unit transfer (FUT, strip method) and follicular unit extraction (FUE, dot excision) methods. In each method of hair transplant, the single unit of hair growth, the follicle, is isolated and implanted to create a result that is natural and lasting. Overall, technological advancements are now fully available to clinicians and have opened a new and exciting chapter in hair restoration.

 
  • 1 Davis DS, Callender VD. Review of quality of life studies in women with alopecia.. Int J Womens Dermatol 2018; 4 (1) 18-22 PubMed (PMID: 29872671)
  • 3 Badran KW, Sand JP. Platelet-rich plasma for hair loss: review of methods and results.. Facial Plast Surg Clin North Am 2018; 26 (4) 469-485 PubMed (PMID: 30213428)
  • 4 Gentile P, Garcovich S, Bielli A, Scioli MG, Orlandi A, Cervelli V. The effect of platelet-rich plasma in hair regrowth: a randomized placebo-controlled trial.. Stem Cells Transl Med 2015; 4 (11) 1317-1323 PubMed (PMID: 26400925)
  • 5 Lin WH, Xiang LJ, Shi HX et al. Fibroblast growth factors stimulate hair growth through β-catenin and Shh expression in C57BL/6 mice.. BioMed Res Int 2015; 2015: 730139 PubMed (PMID: 25685806)
  • 6 McElwee K, Hoffmann R. Growth factors in early hair follicle morphogenesis.. Eur J Dermatol 2000; 10 (5) 341-350 PubMed (PMID: 10882941)
  • 7 Dhurat R, Sukesh M. Principles and methods of preparation of platelet-rich plasma: a review and author’s perspective.. J Cutan Aesthet Surg 2014; 7 (4) 189-197 PubMed (PMID: 25722595)
  • 8 Dohan Ehrenfest DM, Pinto NR, Pereda A et al. The impact of the centrifuge characteristics and centrifugation protocols on the cells, growth factors, and fibrin architecture of a leukocyte- and platelet-rich fibrin (L-PRF) clot and membrane.. Platelets 2018; 29 (2) 171-184 PubMed (PMID: 28437133)
  • 9 Leitner GC, Gruber R, Neumüller J et al. Platelet content and growth factor release in platelet-rich plasma: a comparison of four different systems.. Vox Sang 2006; 91 (2) 135-139 PubMed (PMID: 16907874)
  • 10 Dhillon RS, Schwarz EM, Maloney MD. Platelet-rich plasma therapy: future or trend?. Arthritis Res Ther 2012; 14 (4) 219 PubMed (PMID: 22894643)
  • 11 Marx RE. Platelet-rich plasma (PRP): what is PRP and what is not PRP?. Implant Dent 2001; 10 (4) 225-228 PubMed (PMID: 11813662)
  • 12 Giusti I, Rughetti A, D’Ascenzo S et al. Identification of an optimal concentration of platelet gel for promoting angiogenesis in human endothelial cells.. Transfusion 2009; 49 (4) 771-778 PubMed (PMID: 19170984)
  • 13 Bayat M, Yazdanpanah MJ, Hamidi Alamdari D, Banihashemi M, Salehi M. The effect of platelet-rich plasma injection in the treatment of androgenetic alopecia.. J Cosmet Dermatol 2019; 18 (6) 1624-1628 PubMed (PMID: 30895745)
  • 14 Puig CJ, Reese R, Peters M. Double-blind, placebo-controlled pilot study on the use of platelet-rich plasma in women with female androgenetic alopecia.. Dermatol Surg 2016; 42 (11) 1243-1247 PubMed (PMID: 27608205)
  • 15 Mapar MA, Shahriari S, Haghighizadeh MH. Efficacy of platelet-rich plasma in the treatment of androgenetic (male-patterned) alopecia: a pilot randomized controlled trial.. J Cosmet Laser Ther 2016; 18 (8) 452-455 PubMed (PMID: 27593381)
  • 16 Gupta AK, Versteeg SG, Rapaport J, Hausauer AK, Shear NH, Piguet V. The efficacy of platelet-rich plasma in the field of hair restoration and facial aesthetics: a systematic review and meta-analysis.. J Cutan Med Surg 2019; 23 (2) 185-203 PubMed (PMID: 30606055)
  • 17 Stevens J, Khetarpal S. Platelet-rich plasma for androgenetic alopecia: a review of the literature and proposed treatment protocol.. Int J Womens Dermatol 2018; 5 (1) 46-51 PubMed (PMID: 30809579)
  • 18 Gupta AK, Cole J, Deutsch DP et al. Platelet-rich plasma as a treatment for androgenetic alopecia.. Dermatol Surg 2019; 45 (10) 1262-1273 PubMed (PMID: 30882509)
  • 20 Avram MR, Finney R, Rogers N. Hair transplantation controversies.. Dermatol Surg 2017; 43 (Suppl. Suppl 2) S158-S162 PubMed (PMID: 29064980)
  • 21 Joshi R, Shokri T, Baker A et al. Alopecia and techniques in hair restoration: an overview for the cosmetic surgeon.. Oral Maxillofac Surg 2019; 23 (2) 123-131 PubMed (PMID: 30788753)
  • 24 Umar S. Body hair transplant by follicular unit extraction: my experience with 122 patients.. Aesthet Surg J 2016; 36 (10) 1101-1110 PubMed (PMID: 27241361)
  • 25 Rodman R, Sturm AK. hairline restoration: difference in men and woman-length and shape.. Facial Plast Surg 2018; 34 (2) 155-158 PubMed (PMID: 29631285)
  • 26 Sirinturk S, Bagheri H, Govsa F, Pinar Y, Ozer MA. Study of frontal hairline patterns for natural design and restoration.. Surg Radiol Anat 2017; 39 (6) 679-684 PubMed (PMID: 27830323)
  • 29 Buchwach KA. Graft harvesting and management of the donor site.. Facial Plast Surg Clin North Am 2013; 21 (3) 363-374 PubMed (PMID: 24017978)
  • 30 Farjo B, Farjo N. Dense packing: surgical indications and technical considerations.. Facial Plast Surg Clin North Am 2013; 21 (3) 431-436 PubMed (PMID: 24017984)
  • 32 Adil A, Godwin M. The effectiveness of treatments for androgenetic alopecia: a systematic review and meta-analysis.. J Am Acad Dermatol 2017; 77 (1) 136-141.e5 PubMed (PMID: 28396101)
  • 34 Konior RJ. Complications in hair-restoration surgery.. Facial Plast Surg Clin North Am 2013; 21 (3) 505-520 PubMed (PMID: 24017992)