The effect of autologous leukocyte platelet rich fibrin on the rate of orthodontic tooth movement: A prospective randomized clinical trial

Azita Tehranchi; Hossein Behnia; Fereydoun Pourdanesh; Parsa Behnia; Nelson Pinto; Farnaz Younessian

doi:10.4103/ejd.ejd_424_17

European Journal of Dentistry, Table of Contents

CC BY-NC-ND 4.0 · Eur J Dent 2018; 12(03): 350-357
DOI: 10.4103/ejd.ejd_424_17

Original Article

Dental Investigation Society

The effect of autologous leukocyte platelet rich fibrin on the rate of orthodontic tooth movement: A prospective randomized clinical trial

Azita Tehranchi

¹Dental Research Center, Dental Research Institute, Dental School, Shahid Beheshti University of Medical Sciences, Tehran, Iran

,

Hossein Behnia

²Dentofacial Deformities Research Center, Dental Research Institute, Dental School, Shahid Beheshti University of Medical Sciences, Tehran, Iran

,

Fereydoun Pourdanesh

³Department of Oral and Maxillofacial Surgery, Dental School, Shahid Beheshti University of Medical Sciences, Tehran, Iran

,

Parsa Behnia

⁴Postgraduate Student, Department of Oral and Maxillofacial Surgery, Dental School, Shahid Beheshti University of Medical Sciences, Tehran, Iran

,

Nelson Pinto

⁵Department of Periodontic and Implant Dentistry, Faculty of Dentistry, University of The Andes, Las Condes, Santiago, Chile

,

Farnaz Younessian

⁶Department of Orthodontics, College of Dental Medicine, Nova Southeastern University, Fort Lauderdale, FL 33328, USA

› Author Affiliations

Abstract

ABSTRACT

Objective: The aim of this study was to evaluate the effect of LPRF, placed in extraction sockets, on orthodontic tooth movement (OTM). Materials and Methods: Thirty extraction sockets from eight patients (five males, three females, with a mean age of 17.37 years; range 12–25 years) requiring extraction of first premolars based on their orthodontic treatment plan participated in this split-mouth clinical trial. In one randomly selected quadrant of each jaw, the extraction socket was preserved as the experimental group by immediate placement of LPRF in the extraction socket. The other quadrant served as the control group for secondary healing. Immediately, the teeth adjacent to the defects were pulled together by a NiTi closed-coil spring with constant force. A piece of 0.016 × 0.022-inch stainless steel wire was used as the main arch wire. The amount of OTM was measured on the study casts at eight time points with 2-week intervals for 3 months. Analysis of random effect model was performed for the purpose of comparison between the experimental and control groups. Results: According to the random effect model, a statistically significant difference was found between the experimental and control group in rate of OTM (P = 0.006). Conclusion: According to the results, application of LPRF, as an interdisciplinary approach combining orthodontics and surgery, may accelerate OTM, particularly in extraction cases.

Key words:

Leukocyte platelet rich fibrin - orthodontic tooth movement - plasma - platelet concentrate - platelet-rich fibrin - platelet-rich plasma

Full Text

References

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