The rationale behind novel bone grafting techniques in small animals

G. R. Ragetly; D. J. Griffon

doi:10.3415/VCOT-10-03-0040

Veterinary and Comparative Orthopaedics and Traumatology, Table of Contents

Vet Comp Orthop Traumatol 2011; 24(01): 1-8
DOI: 10.3415/VCOT-10-03-0040

Review Article

Schattauer GmbH

The rationale behind novel bone grafting techniques in small animals

Authors

G. R. Ragetly

¹Department of Veterinary Clinical Medicine, University of Illinois, Urbana, Illinois, USA
D. J. Griffon

¹Department of Veterinary Clinical Medicine, University of Illinois, Urbana, Illinois, USA

Abstract

Summary

Autograft is considered ideal for grafting procedures, providing osteoinductive growth factors, osteogenic cells, and an osteoconductive scaffold. Limitations, however, exist regarding donor site morbidity and graft availability. Although allograft provides an osteoconductive matrix with some osteoinductivity, its availability is limited. To achieve optimal bone graft properties, researchers are developing new materials with the goal of designing synthetics as close to autograft as possible while still facilitating their clinical use. However, the constant evolution of internal fixation stimulates the search for growth factors and cells which could stimulate bone healing.

Keywords

Bone grafting - osteogenesis - allograft - osteoconductive material - bone morphogenetic proteins

Full Text

References

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