Download PDF
Planta Med 1990; 56(2): 164-167
DOI: 10.1055/s-2006-960916
Papers

© Georg Thieme Verlag Stuttgart · New York

Antiplatelet Components in Panex ginseng

Sheng-Chu Kuo1 , Che-Ming Teng2 , Jang-Chang Lee1 , Feng-Nien Ko2 , Sheng-Chih Chen1 , Tian-Shung Wu3
  • 1Graduate Institute of Pharmaceutical Chemistry, China Medical College, 91 Hsueh Shih Road, Taichung, Taiwan, Republic of China
  • 2Pharmacological Institute, College of Medicine, National Taiwan University, Taipei, Taiwan, Republic of China
  • 3Department of Chemistry, National Cheng Kung University, Tainan, Taiwan, Republic of China
Further Information

Publication History

1988

Publication Date:
05 January 2007 (online)

Also available at
 PDF Download  Permissions and Reprints
Preview

Abstract

Panaxynol and ginsenosides Ro, Rg1, and Rg2 were found to be the main antiplatelet components in the diethyl ether and 1-butanol fractions, respectively, during the activity-guided fractionation of Panax ginseng, Panaxynol inhibited the aggregation, release reaction, and thromboxane formation in rabbit platelets while ginsenosides Ro, Rg1 and Rg2 suppressed the release reaction only.

Key words

Panaxynol - ginsenosides - antiplatelet activity - aggregation activity - ATP release - thromboxane formation