Zusammenfassung:
Die diabetische autonome Neuropathie (DAN) ist die häufigste autonome Neuropathie
der westlichen Welt. Ihre Symptome sind vielfältig und betreffen nahezu alle Organsysteme.
Im Vordergrund stehen dabei kardiovaskuläre Störungen wie eingeschränkte Herzfrequenzvariabilität
und pathologische Orthostasereaktion. Ihre Diagnostik erfolgt im Wesentlichen durch
die Analyse kardiovaskulärer Stimulationsmanöver. Nachfolgend soll ein Einblick in
Epidemiologie, Klinik, Diagnostik, Pathogenese, Therapiemöglichkeiten und Prognose
der diabetischen autonomen Neuropathie vermittelt werden.
Diabetic Autonomic Neuropathy:
Diabetic autonomic neuropathy is the most frequent autonomic neuropathy in western
countries. Diabetic autonomic neuropathy affects almost every organ. Among the most
common symptoms are cardiovascular disturbances such as reduced heart rate variability
and pathologic orthostatic reaction. The diagnosis of diabetic autonomic neuropathy
is mainly based on the analysis of cardiovascular challenge maneuvers. The following
article describes epidemiology, clinical findings, diagnosis, pathogenesis, therapeutic
options and prognosis in diabetic autonomic neuropathy.
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Prof. Dr. med. Max J. Hilz
Neurologische Klinik mit Poliklinik der Universität Erlangen-Nürnberg
Schwabachanlage 6
91054 Erlangen
