Pseudotumor Cerebri Caused by SARS-CoV-2 Infection in a Boy

Abstract

In this case report, we present the case of a 7-year-old male patient who started with diplopia and paralysis of the sixth unilateral cranial nerve after a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The cranial resonance was normal and the cerebrospinal pressure was 32 cm H₂O detected by lumbar puncture. The treatment with corticosteroids and acetazolamide was effective. This is the first case of idiopathic intracranial hypertension associated to SARS-CoV-2 probably due to immune-mediated process.

Keywords

pseudotumor cerebri - idiopathic intracranial hypertension - SARS-CoV-2 - Mycoplasma pneumoniae

Publication History

Received: 11 June 2020

Accepted: 08 July 2020

Article published online:
02 September 2020

• References

• 1 Shi Y, Wang Y, Shao C. et al. COVID-19 infection: the perspectives on immune responses. Cell Death Differ 2020; 27 (05) 1451-1454
• 2 Mao L, Jin H, Wang M. et al. Neurologic manifestations of hospitalized patients with coronavirus disease 2019 in Wuhan, China. JAMA Neurol 2020; e201127
• 3 Burkett JG, Ailani J. An up to date review of pseudotumor cerebri syndrome. Curr Neurol Neurosci Rep 2018; 18 (06) 33
• 4 Mosquera Gorostidi A, Iridoy Zulet M, Azcona Ganuza G, Gembero Esarte E, Yoldi Petri ME, Aguilera Albesa S. Pseudotumour cerebri in children: aetiology, clinical features, and progression. Neurologia 2019; 34 (02) 89-97
• 5 Ravid S, Shachor-Meyouhas Y, Shahar E, Kra-Oz Z, Kassis I. Viral-induced intracranial hypertension mimicking pseudotumor cerebri. Pediatr Neurol 2013; 49 (03) 191-194
• 6 Fan BE, Lim KGE, Chong VCL, Chan SSW, Ong KH, Kuperan P. COVID-19 and mycoplasma pneumoniae coinfection. Am J Hematol 2020; 95 (06) 723-724