Imaging Evaluation of Disorders of Sex Development

Anu Eapen; Anuradha Chandramohan; Betty Simon; Tharani Putta; Reetu John; Aruna Kekre

doi:10.1055/s-0039-3402101

Journal of Gastrointestinal and Abdominal Radiology, Table of Contents

CC BY-NC-ND 4.0 · Journal of Gastrointestinal and Abdominal Radiology 2020; 03(02): 181-192
DOI: 10.1055/s-0039-3402101

Review Article

Imaging Evaluation of Disorders of Sex Development

Anu Eapen

¹Department of Radiology, Christian Medical College, Vellore, Tamil Nadu, India

,

Anuradha Chandramohan

¹Department of Radiology, Christian Medical College, Vellore, Tamil Nadu, India

,

Betty Simon

¹Department of Radiology, Christian Medical College, Vellore, Tamil Nadu, India

,

Tharani Putta

¹Department of Radiology, Christian Medical College, Vellore, Tamil Nadu, India

,

Reetu John

¹Department of Radiology, Christian Medical College, Vellore, Tamil Nadu, India

,

Aruna Kekre

²Department of Obstetrics and Gynaecology, Christian Medical College, Vellore, Tamil Nadu, India

› Author Affiliations

Abstract

Disorders of sex development (DSD) refer to congenital conditions with a typical development of chromosomal, gonadal, or anatomic sex. In the revised classification of DSD, there are three categories based on karyotype: 46,XX DSD; 46,XY DSD; and sex chromosome DSD. Imaging, as part of a multidisciplinary approach to management of DSD, has a key role in gender assignment. The main role of imaging is to help in identifying the gonads and the Müllerian structures. Ultrasound is useful, especially in the neonate with ambiguous genitalia. Magnetic resonance imaging is a useful modality to locate and characterize the gonads in young girls with primary amenorrhea and also to identify streak gonads, which have a risk of malignancy.

Keywords

disorders of sex development - DSD - imaging - ambiguous genitalia - gonads

Full Text

References

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