ABSTRACT
Objectives: The aim of this study was to evaluate the efficiency of ozone alone and
with a re-mineralizing solution following application on initial pit and fissure caries
lesions in permanent molars. Methods: Forty children (9-12 years) having non-cavitated
fissure caries lesions on bilateral 40 first permanent mandibular molar teeth were
participated in the study. Patients were randomly allocated to 2 experimental groups
consisting of 20 subjects. In the first group, ozone was applied once for 40 seconds
to the assigned test teeth of each pair. In the second group, ozone was applied once
for 40 seconds to the assigned test teeth of each pair with the use of re-mineralizing
solution. Progression or improvement of the caries was assessed at baseline, immediately
after treatment and at 1-,2-,3-, and 6 month follow-up by comparing the DIAGNOdent
values, Clinical Severity Indexes, Oral Hygiene Scores. The results were analyzed
statistically by using the Wilcoxon-Test for dependent samples in each group. When
comparing different test groups (control and experimental groups) the Friedman S test
followed by the Mann-Whitney U test was used. Results: A statistically significant
difference was found between all of the control and experimental test lesions in each
group (P<.001). However, there was no statistically significant difference between
the ozone treated groups and those using the additional re-mineralizing solution (P>.001).
Conclusions: Ozone treatment either alone or combined with a re-mineralizing solution
was found to be effective for remineralization of initial fissure caries lesions.
(Eur J Dent 2011;5:393-399)
Key words:
Ozone - Fissure caries - Preventive dentistry