Pharmacokinetics of Saruplase, a Recombinant Unglycosylated Human Single-Chain Urokinase-Type
Plasminogen Activator and Its Effects on Fibrinolytic and Haemostatic Parameters in
Healthy Male Subjects
A de Boer
1
The Centre for Human Drug Research, University Hospital Leiden, The Netherlands
,
C Kluft
2
The Gaubius Laboratory, IVVO-TNO, Leiden, The Netherlands
,
J Gerloff
3
The Grünenthal GmbH, Aachen, Germany
,
G Dooijewaard
1
The Centre for Human Drug Research, University Hospital Leiden, The Netherlands
,
W A Günzler
3
The Grünenthal GmbH, Aachen, Germany
,
H Beier
3
The Grünenthal GmbH, Aachen, Germany
,
F J M van der Meer
4
The Thrombosis Service, Leiden, The Netherlands
,
A F Cohen
1
The Centre for Human Drug Research, University Hospital Leiden, The Netherlands