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Thromb Haemost 1994; 72(06): 843-847
DOI: 10.1055/s-0038-1648972
Original Article
Schattauer GmbH Stuttgart

α1-Antitrypsin Pittsburgh (Met358 → Arg) Inhibits the Contact Pathway of Intrinsic Coagulation and Alters the Release of Human Neutrophil Elastase during Simulated Extracorporeal Circulation

Autoren

  • Yanina T Wachtfogel

    1   Sol Sherry Thrombosis Research Center and the Hematology Division, Departments of Medicine and Physiology, Temple University School of Medicine, Philadelphia, PA, USA
  • Rainer Bischoff

    2   Transgene SA, Strasbourg, France
  • Ross Bauer

    3   Division of Cardiothoracic Surgery, Harrison Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, USA
  • C Erik Hack

    4   Central Laboratory of The Netherlands Red Cross, Blood Transfusion Service and Laboratory for Experimental and Clinical Immunology, University of Amsterdam, Amsterdam, The Netherlands
  • Jan H Nuijens

    5   Gene Pharming Europe BV, Leiden, The Netherlands
  • Umberto Kucich

    6   Research Division, Department of Medicine, The Graduate Hospital, Philadelphia, PA, USA
  • Stefan Niewiarowski

    1   Sol Sherry Thrombosis Research Center and the Hematology Division, Departments of Medicine and Physiology, Temple University School of Medicine, Philadelphia, PA, USA
  • L Henry Edmunds Jr

    3   Division of Cardiothoracic Surgery, Harrison Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, USA
  • Robert W Colman

    1   Sol Sherry Thrombosis Research Center and the Hematology Division, Departments of Medicine and Physiology, Temple University School of Medicine, Philadelphia, PA, USA