How Much Factor V Is Enough?

 

^* Manuscript in Preparation, Hockin M, Smith T, Cawthern K, Mann KG.

• References

• 1 Yang TL, Cui J, Taylor JM, Yang A, Gruber SB, Ginsburg D. Rescue of fatal neonatal hemorrhage in factor V deficient mice by low level transgene expression. Thromb Haemost 2000; 83: 70-7.
• 2 Tracy PB, Eide LL, Bowie EJW, Mann KG. Radioimmunoassay of Factor V in Human Plasma and Platelets. Blood 1982; 60: 59-63.
• 3 Rand MD, Lock JB, van’t Veer C, Gaffney DP, Mann KG. Blood Clotting in Minimally Altered Whole Blood. Blood 1996; 88: 3432-45.
• 4 Krishnaswamy S, Nesheim ME, Pryzdial ELG, Mann KG. Assembly of Prothrombinase Complex. For Proteolytic Enzymes in Coagulation, Fibrinolysis, and Complement Activation. Methods in Enzymology. Vol. 222, Part A (15): 261-80 Lorand L, Mann KG. eds. New York: Academic Press; 1993
• 5 Nicols WC, Amano K, Cacheris PM, Figueiredo MS, Michaelides K, Schwaab R, Hoyer L, Kaufman RJ, Ginsburg D. Moderation of hemophilia A phenotype by the factor V R506Q mutation. Blood 1996; 88: 1183.
• 6 van’t Veer C, Golden NJ, Kalafatis M, Siminoi P, Bertina RM, Mann KG. An In Vitro Analysis of the Combination of Hemophilia A and Factor Vleiden. Blood 1997; 90: 3067-72.