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Semin Thromb Hemost 2015; 41(01): 043-048
DOI: 10.1055/s-0034-1398380
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Hypercoagulability and Venous Thromboembolism in Burn Patients

Jonathan P. Meizoso
1   Divisions of Trauma, Surgical Critical Care, and Burns at the Ryder Trauma Center, The DeWitt Daughtry Family Department of Surgery, University of Miami Leonard M. Miller School of Medicine, Miami, Florida
,
Juliet J. Ray
1   Divisions of Trauma, Surgical Critical Care, and Burns at the Ryder Trauma Center, The DeWitt Daughtry Family Department of Surgery, University of Miami Leonard M. Miller School of Medicine, Miami, Florida
,
Casey J. Allen
1   Divisions of Trauma, Surgical Critical Care, and Burns at the Ryder Trauma Center, The DeWitt Daughtry Family Department of Surgery, University of Miami Leonard M. Miller School of Medicine, Miami, Florida
,
Robert M. Van Haren
1   Divisions of Trauma, Surgical Critical Care, and Burns at the Ryder Trauma Center, The DeWitt Daughtry Family Department of Surgery, University of Miami Leonard M. Miller School of Medicine, Miami, Florida
,
Gabriel Ruiz
1   Divisions of Trauma, Surgical Critical Care, and Burns at the Ryder Trauma Center, The DeWitt Daughtry Family Department of Surgery, University of Miami Leonard M. Miller School of Medicine, Miami, Florida
,
Nicholas Namias
1   Divisions of Trauma, Surgical Critical Care, and Burns at the Ryder Trauma Center, The DeWitt Daughtry Family Department of Surgery, University of Miami Leonard M. Miller School of Medicine, Miami, Florida
,
Carl I. Schulman
1   Divisions of Trauma, Surgical Critical Care, and Burns at the Ryder Trauma Center, The DeWitt Daughtry Family Department of Surgery, University of Miami Leonard M. Miller School of Medicine, Miami, Florida
,
Louis R. Pizano
1   Divisions of Trauma, Surgical Critical Care, and Burns at the Ryder Trauma Center, The DeWitt Daughtry Family Department of Surgery, University of Miami Leonard M. Miller School of Medicine, Miami, Florida
,
Kenneth G. Proctor
1   Divisions of Trauma, Surgical Critical Care, and Burns at the Ryder Trauma Center, The DeWitt Daughtry Family Department of Surgery, University of Miami Leonard M. Miller School of Medicine, Miami, Florida
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Publikationsdatum:
15. Januar 2015 (online)

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Abstract

To our knowledge, this is the first comprehensive review on the subject of venous thromboembolism (VTE) and hypercoagulability in burn patients. Specific changes in coagulability are reviewed using data from thromboelastography and other techniques. Disseminated intravascular coagulation in burn patients is discussed. The incidence and risk factors associated with VTE in burn patients are then examined, followed by the use of low-molecular-weight heparin thromboprophylaxis and monitoring techniques using antifactor Xa levels. The need for large, prospective trials in burn patients is highlighted, especially in the areas of VTE incidence and safe, effective thromboprophylaxis.

Keywords

burns - thrombosis - venous thromboembolism - hypercoagulability - enoxaparin