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Planta Med 2019; 85(17): 1292-1303
DOI: 10.1055/a-0947-5712
DOI: 10.1055/a-0947-5712
Biological and Pharmacological Activity
Reviews
Neuroprotective Potential of Ginkgo biloba in Retinal Diseases
Further Information
Publication History
received 22 March 2019
revised 22 May 2019
accepted 02 June 2019
Publication Date:
02 July 2019 (online)
Abstract
Like other tissues of the central nervous system, the retina is susceptible to damage by oxidative processes that result in several neurodegenerative disease such as age-related macular degeneration, diabetic retinopathy, glaucoma, ischaemic retinal disease, retinal disease produced by light oxidation, and detached retina, among other diseases. The use of antioxidant substances is a solution to some health problems caused by oxidative stress, because they regulate redox homeostasis and reduce oxidative stress. This is important for neurodegeneration linked to oxidation processes. In line with this, Ginkgo biloba is a medicinal plant with excellent antioxidant properties whose effects have been demonstrated in several degenerative processes, including retinal diseases associated with neurodegeneration. This review describes the current literature on the role of ginkgo in retinal diseases associated with neurodegeneration. The information leads to the conclusion that G. biloba extracts might be a good option to improve certain neurodegenerative retinal diseases, but more research is needed to determine the safety and efficacy of G. biloba in these retinal degenerative processes.
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