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Synfacts 2008(7): 0774-0774  
DOI: 10.1055/s-2008-1078438
Polymer-Supported Synthesis
© Georg Thieme Verlag Stuttgart · New York

InCl3/SiO2-Catalyzed Hydroarylation

Contributor(s): Yasuhiro Uozumi, Go Hamasaka
G. Sun, H. Sun, Z. Wang*, M.-M. Zhou*
University of Science and Technology of China, Hefei, P. R. of China and New York University, USA
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Publication History

Publication Date:
20 June 2008 (online)

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Significance

InCl3/SiO2-catalyzed highly regio­selective hydroarylation of styrenes with arenes affording 1,1-diarylalkanes was described. The InCl3/SiO2 catalyst was prepared by adding SiO2 (500 mg, 200-300 mesh) to a solution of InCl3 (1 mmol) in CHCl3 (10 mL) followed by evaporation of the solvent in vacuo. The hydroarylation of styrenes with arenes was carried out in the presence of 5 mol% of IrCl3/SiO2 under solvent-free conditions to give the corresponding 1,1-diarylalkane compounds in 50-95% yield with high regio­selectivity (21 examples).