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Planta Med 1986; 52(4): 260-262
DOI: 10.1055/s-2007-969146
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© Georg Thieme Verlag Stuttgart · New York

Hypoglycemic Activity of Salvia lavandulifolia

J. Jimenez, S. Risco, T. Ruiz, A. Zarzuelo
  • Department of Pharmacognosy and Pharmacodynamics, Faculty of Pharmacy, University of Granada, Granada, Spain.
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Publikationsverlauf

1985

Publikationsdatum:
26. Februar 2007 (online)

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Abstract

The hypoglycemic activity of infusions and suspensions of Salvia lavandulifolia was studied in normoglycemic, hypoglycemic, and alloxan-diabetic rabbits. Variations in circulating levels of insulin were also studied in normoglycemic animals. The greatest decreases in glucose levels (17-18%) were obtained with doses > 0.250 mg/kg in normoglycemic rabbits. No effect was seen on insulin levels. In glucose-induced hyperglycemia, antidiabetic activity was seen only when the Salvia infusion was administered simultaneously with glucose. In alloxan-diabetic rabbits, the daily administration of 0.250 mg/kg of infusion resulted in a 33% decrease in blood glucose levels.

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