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Horm Metab Res 1987; 19(8): 364-366
DOI: 10.1055/s-2007-1011825
ORIGINALS

© Georg Thieme Verlag, Stuttgart · New York

Effect of Calcitonin on the Prolactin Surge of Proestrus

M. Cressent1 , C. Elie2 , G. Milhaud1
  • 1Faculté de Médecine Saint-Antoine, Laboratoire de Biophysique, Paris, France
  • 2Faculté de Médecine Saint-Antoine, Laboratoire d'Histologie, Paris, France
Further Information

Publication History

1985

1986

Publication Date:
14 March 2008 (online)

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Summary

The effect of calcitonin (CT) on the prolactin (PRL) surge of proestrus in rats was investigated under normal and perturbed lighting conditions. Salmon calcitonin (SCT) was injected i.p. on diestrus 2 or on proestrus, plasma PRL levels were measured by radioimmunoassay. SCT had no effect on the PRL surge under normal lighting conditions but it induced a small drop in PRL level measured on proestrus morning, 3 hours after CT injection.

Animals submitted to perturbed light conditions had higher PRL levels than those kept under normal lighting. These data would indicate that for the female rats on proestrus the sensitivity to stress due to injection and blood sampling may be modulated by changing the photoperiod. SCT injection under these conditions may facilitate this destabilization in PRL level.

Key-Words

CT Action - PRL Surge - Stress - Light Stimulation

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