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Planta Med 1989; 55(3): 271-272
DOI: 10.1055/s-2006-962001
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© Georg Thieme Verlag Stuttgart · New York

An Antitumor Principle from Euphorbia lathyris

Hideji Itokawa, Yoshitatsu Ichihara, Kinzo Watanabe, Koichi Takeya
  • Department of Pharmacognosy, Tokyo College of Pharmacy, Horinouchi 1432-1, Hachioji, 192-03 Tokyo, Japan
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Publication History

1988

Publication Date:
24 January 2007 (online)

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Abstract

The extract of seeds of Euphorbia lathyris L. showed antitumor activity against Sarcoma 180 ascites in mice. Systematic fractionation of the extract led to the characterization of ingenol-3-hexadecanoate as an active principle, together with an inactive diterpene ingenol-20-hexadecanoate.

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