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Planta Med 1998; 64(5): 479-481
DOI: 10.1055/s-2006-957492
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© Georg Thieme Verlag Stuttgart · New York

Bioassay Guided Isolation of a New C18-Polyacetylene, (+)-9(Z),17-Octadecadiene-12,14-diyne-1,11,16-triol, from Cassonia barteri

S. Papajewski1 , J. H. Guse1 , I. Klaiber1 , G. Roos1 , R. Süßmuth2 , B. Vogler1 , C. U. Walter1 , W. Kraus1
  • 1Institut für Chemie, Lehrstuhl für Organische Chemie, Universität Hohenheim, Stuttgart, Germany
  • 2Institut fšr Mikrobiologie, Universität Hohenheim, Stuttgart, Germany
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Publikationsverlauf

1997

1998

Publikationsdatum:
04. Januar 2007 (online)

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Abstract

A novel C18-polyacetylene, (+)-9(Z),17-octadecadiene-12,14-diyne-1,11,16-triol (3), has been isolated from the ethyl acetate extract of Cassonia barteri (Araliaceae) leaves collected in Cameroon. The structure determination was achieved by NMR, mass, IR, and UV spectroscopy. The new polyenyne shows antibacterial activity against Bacillus subtilis and Pseudo-monas fluorescens, antifungal activity against Cladosporium cucumerinum, moiluscicidal activity against Biomphalaria glabrata at low concentrations, and in addition it possesses haemolytic activity.

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