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Horm Metab Res 1972; 4(3): 149-151
DOI: 10.1055/s-0028-1094089
DOI: 10.1055/s-0028-1094089
Originals
© Georg Thieme Verlag KG Stuttgart · New York
Effect of lodination on the Biological Activity of Insulin
Further Information
Publication History
Publication Date:
07 January 2009 (online)
Abstract
The preparation of pure 125I-monoiodoinsulin is described. This iodohormone has lost its capacity to stimulate the glucose uptake by rat diaphragm, nevertheless it binds to the plasmatic receptors and competes with unlabeled insulin.
Key words
Monoiodoinsulin - Bioactivity - Binding Constants - Inhibitory Effect