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Horm Metab Res 1972; 4(4): 296-300
DOI: 10.1055/s-0028-1094071
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© Georg Thieme Verlag KG Stuttgart · New York

Lack of Effect of Thyrocalcitonin on Formation of Bone Matrix in Mice and Rats

S. C. Marks [*]  Jr. 
  • Naval Medical Research Institute, National Naval Medical Center, Bethesda, Maryland and Dept. of Anatomy, University of Massachusetts Medical School, Worcester, Massachusetts
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Publication History

Publication Date:
07 January 2009 (online)

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Abstract

The ability of thyrocalcitonin to promote bone formation has been tested in thyroparathyroidectomized mice and rats by measuring the incorporation of 3H-proline into calvarial bone matrix. It is concluded that porcine thyrocalcitonin has little or no direct effect on bone formation in these species.

Key words

Parathyroid Extract (PTE) - Thyroxine (T4) - Thyrocalcitonin (TCT) - Bone Matrix Formation - Thyroparathyroidectomy - Rat - Mouse

1 Present address: Department of Anatomy, University of Massachusetts, Medical School, Worcester, Massachusetts, USA