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Planta Med 2023; 89(01): 19-29
DOI: 10.1055/a-1663-6461
Biological and Pharmacological Activity
Reviews

New Perspectives for the Use of Potentilla alba Rhizomes to Treat Thyroid Gland Impairments

Daniel Augustynowicz
1   Department of Pharmacognosy, Faculty of Pharmacy with the Division of Laboratory Medicine, Medical University of Białystok, Białystok, Poland
,
Magdalena Podolak
2   Studentʼs Scientific Association, Department of Pharmacognosy, Medical University of Białystok, Białystok, Poland
,
Klaus Peter Latté
3   Warägerweg 21, Berlin, Germany
,
Michał Tomczyk
1   Department of Pharmacognosy, Faculty of Pharmacy with the Division of Laboratory Medicine, Medical University of Białystok, Białystok, Poland
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Abstract

Potentilla alba is a valuable medicinal plant that has been highly praised even before its first appearance in herbal books; however, it has now been forgotten in Western Europe. Currently, this species is used in Eastern Europe as a remedy to treat dysentery and various thyroid gland dysfunctions. The present review summarizes the advances in the phytochemical, pharmacological, and toxicological research related to this plant species. Clinical trials that have been conducted to date support its traditional use for treating thyroid disorders, although its exact mechanism of action, bioavailability, and pharmacokinetics data are missing.

Key words

Potentilla alba - Rosaceae - phytochemical profile - pharmacology - thyrotropic activity


Publication History

Received: 28 July 2021

Accepted after revision: 27 September 2021

Article published online:
29 October 2021

© 2021. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

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